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Mikhail Nikiforov
Roswell Park Cancer Institute

Mikhail A. Nikiforov, Ph.D. is Associate Professor of Oncology, Department of Cell Stress Biology, Roswell Park Cancer Institute.

Misha’s research program is focused on several aspects of molecular biology and drug resistance of melanoma and several blood malignancies including:

• Elucidation of molecular mechanisms underlying oncogene-dependent senescence in normal human melanocytes and melanoma cells
• Acquisition of invasive phenotypes by melanoma cells
• The role of Krüppel-like transcription factors in the regulation of therapeutic outcomes in multiple myeloma, acute promyelocytic leukemia, and acute myeloid leukemia

In parallel, his lab is actively pursuing the development of a novel class of small molecule inhibitors of C-MYC, an oncogenic transcription factor that is overexpressed in more than 80% of human cancers. His research is funded by the National Cancer Institute, American Cancer Society, and by private biomedical companies.

Education and Training:

B.S./M.S. in Biochemistry, Moscow State University, Moscow, Russia 1992
PhD (Genetics) University of Illinois at Chicago 1997
Postdoctoral Fellow, University of Rochester, Department of Biology 1997-2000
Research Associate, Princeton University, Department of Molecular Biology 2000-2004
Assistant Professor, University of Michigan, Department of Dermatology 2004-2007